Tyronn Lue attended Raytown High School in Missouri. He later went to University of Nebraska, where he attended his freshman and sophomore years. He played basketball and studied Sociology. He finished his Nebraska career ranked third on the all-time list in assists (432), fourth in three-pointers made (145) and attempted (407), fifth in steals (154) and seventh in scoring (1,577). He led the Cornhuskers in assists in each of his three seasons, and finished his career tied with former NBA player Dave Hoppen for most games with 30 or more points, seven.
Lue opted for early entry into the 1998 NBA Draft. He was selected 23rd overall by the Denver Nuggets, but was traded to the Los Angeles Lakers with Tony Battie in exchange for Nick Van Exel on draft night. His first three years with the Lakers were disappointing. He did not get enough playing time and was suffering injuries throughout the year while the Lakers won the NBA championship in 2000. For the 2001 playoffs, Lue excelled and helped the Lakers repeat as champions. Due to his quickness, he was specifically used to guard Allen Iverson in the NBA Finals.
In the summer of 2001, Lue signed with the Washington Wizards where he got considerably more playing time and became a better player at the point. He played with the Orlando Magic in 2003-04 where he got to play a lot of minutes alongside Tracy McGrady while leading the team to the worst record in the NBA that season: 20-62. After the season Lue, along with Juwan Howard and Tracy McGrady were traded to the Houston Rockets for Steve Francis, Cuttino Mobley and Kelvin Cato. In Houston, Lue did not get many minutes of playing time because of the number of point guards the Rockets have on their roster. He was traded during the mid-season to the Atlanta Hawks for Jon Barry. Lue starred in Atlanta, although he again led the team with the worst record in the NBA that year, and the worst record in franchise history: 13-69.
Later, Lue had a verbal agreement to sign with the Los Angeles Lakers when signing period started. Lue continues to play for the Atlanta Hawks.